HDL-C

Biomarker10 papers2 findings

  • Humans8

Associations

2

Alzheimer's disease

upin humans1OR 1.09

1 study
  1. HDL-C is associated with Alzheimer's disease in humans (OR 1.09, 95% CI 1.00-1.19).

    Humans

    Global, Regional and National burden of dementia attributable to metabolic dysregulation from 1990 to 2021, with projections of burden to 2050: An analysis of the global burden of disease study 2021 · Diabetes & metabolic syndrome · 23 Sep 2026

Alzheimer's disease →

Recurrence of colorectal adenomatous polyps

upin humans1

1 study
  1. HDL-C raises the risk of recurrence of colorectal adenomatous polyps in humans.

    “Abnormal high-density lipoprotein cholesterol (HDL-C), higher baseline polyp count, and larger total polyp volume were independent risk factors for adenoma recurrence.”

    Humanspost-polypectomy

    Machine Learning-Based Investigation of Factors Influencing Recurrence of Colorectal Adenomatous Polyps: A Retrospective Cohort Study · Cancers · 17 Sep 2026

Recurrence of colorectal adenomatous polyps →

Latest

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Frontiers in Public HealthHumans

High HbA1c-to-HDL-C ratio linked to CVD risk in older adults

Older adults in the highest ratio quartile had a higher risk of incident cardiovascular disease than those in the lowest (HR = 2.111) over five years.Older adults in the highest ratio quartile had a higher risk of incident cardiovascular disease than those in the lowest (HR = 2.111) over five years.

Advanced ScienceIn silico

Facial foundation model estimates clinical biomarkers

Pretrained on 10 million images, the model assessed 62 biomarkers across eight physiological systems, reaching a median Pearson's r of 0.172 across…Pretrained on 10 million images, the model assessed 62 biomarkers across eight physiological systems, reaching a median Pearson's r of 0.172 across four cohorts.

Journal of Clinical LipidologyHumans

Estimated sdLDL-C predicts cardiovascular risk in Japanese adults

In over 1.8 million Japanese adults, the highest quartile of estimated sdLDL-C carried an ASCVD hazard ratio of 1.25 compared with the lowest.In over 1.8 million Japanese adults, the highest quartile of estimated sdLDL-C carried an ASCVD hazard ratio of 1.25 compared with the lowest.