Growth hormone axis
Pathway2 papers
- Animals2
Latest
2AnimalsPeer-reviewed
Protein Grtp1 protects male germlines from aging and prevents offspring behavioral deficits
Growth hormone treatment rescues germline redox balance and sperm quality in aged males through a Grtp1-dependent mechanism.
Advanced science (Weinheim, Baden-Wurttemberg, Germany) · Liu Y et al.
Deleting liver growth hormone receptors accelerates aging phenotypes and shortens lifespan in mice
The loss of hepatic growth hormone signaling disrupts lipid metabolism and causes mitochondrial damage that can be counteracted by inhibiting PDK4.
Aging cell · Yang K et al.