Sex hormone signalling (oestrogen, androgen)
Pathway7 papers
- Humans1
- Animals2
- Cells3
Latest
7Tamoxifen causes temporary ovarian disruption without altering long-term mouse aging trajectories
A new preprint shows tamoxifen-inducible mouse models remain valid for ovarian aging research despite transient disruptions to estrous cycling.
bioRxiv : the preprint server for biology · Badillo S et al.
Sympathetic nerve aging in mouse skin is sexually dimorphic and reversible
Male mice experience greater distal axon withdrawal that can be reversed by targeting muscle niches with nerve growth factor.
bioRxiv : the preprint server for biology · Pangilinan GR et al.
Ormeloxifene, a non-steroidal selective estrogen receptor modulator induces senescence in breast cancer cells
Androgen receptor polyglutamine tract controls muscle growth and atrophy pathways
Researchers found that expanding polyglutamine tracts in the androgen receptor shift binding toward senescence-linked enhancers, driving muscle atrophy in cells and mice.
bioRxiv · Grafton F et al.
Human vellus hair units undergo cellular and metabolic remodeling during skin aging
A single-nucleus atlas reveals stem cell loss, altered sebocyte activity, and shifted immune interactions in the hair follicles of older men.
Advanced science (Weinheim, Baden-Wurttemberg, Germany) · Li Y et al.