Crispr/cas9
3 papers1 finding
- Funders: National Eye Institute and 2 more
Outcomes
1Toxic protein aggregration
downin reviews1
1 study
Toxic protein aggregration
downin reviews1
Crispr/cas9 decreases toxic protein aggregration.
“CRISPR/Cas9 disruption of mutant APP, Tau, and LRRK2 genes, reducing toxic protein aggregration in AD models has restored normal genetic function.”
Reviewin AD models
Ageing research reviews17 Oct 2025
Funding
3 grants since 2023National Heart, Lung, and Blood InstituteUS$624.2kNational Institute of General Medical SciencesUS$118.2kNational Eye InstituteUS$88.6k
National Heart, Lung, and Blood InstituteClemson UniversityUS$624.2k2024–2028
Dual CRISPR/Cas9 exon deleting approach for the treatment of USH2A-associated disorders
National Eye InstituteMassachusetts Eye and Ear InfirmaryUS$88.6k2021–2028
Uncovering cell-intrinsic restrictions to CRISPR-Cas9 gene editing
National Institute of General Medical SciencesUniversity of California, BerkeleyUS$118.2k2022–2023
Latest
1 in 12 monthsFrontiers in Immunology
Inflammaging and osteoarthritis - therapeutic opportunities
ReviewInflammation
Frontiers in Cellular Neuroscience