LCN2
Gene1 paper3 findingsHGNC 6526NCBI Gene 3934Taxon 9606
- Animals1
Effects
2Pyroptosis
upin mice1
1 study
Pyroptosis
upin mice1
LCN2 induces pyroptosis in mice.
Animalsunilateral nephrectomy model of POCD
Silencing LCN2 eases postoperative cognitive deficits in mice · Research Square · 1 Oct 2026 · Preprint
Cognitive function
downin mice1
1 study
Cognitive function
downin mice1
LCN2 impairs cognitive function in mice.
Animalsunilateral nephrectomy model of POCD
Silencing LCN2 eases postoperative cognitive deficits in mice · Research Square · 1 Oct 2026 · Preprint
Upstream
1TLR3
upin mouse cells1
1 study
TLR3
upin mouse cells1
TLR3 increases LCN2 in mouse cells.
CellsBV2 microglia
Silencing LCN2 eases postoperative cognitive deficits in mice · Research Square · 1 Oct 2026 · Preprint
Latest
1Silencing LCN2 eases postoperative cognitive deficits in mice
AAV-mediated knockdown of LCN2 in aged mice limited microglial inflammation, reduced neuronal pyroptosis, and rescued memory following surgery.AAV-mediated knockdown of LCN2 in aged mice limited microglial inflammation, reduced neuronal pyroptosis, and rescued memory following surgery.