Pyroptosis

ProcessChronic inflammation1 paper1 findingMeSH D000069292GO 0070269

  • Animals1

Upstream

1

LCN2

upin mice1

1 study

  1. LCN2 induces pyroptosis in mice.

    Animalsunilateral nephrectomy model of POCD

    Silencing LCN2 eases postoperative cognitive deficits in mice · Research Square · 1 Oct 2026 · Preprint

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Research SquareAnimalsPreprint

Silencing LCN2 eases postoperative cognitive deficits in mice

AAV-mediated knockdown of LCN2 in aged mice limited microglial inflammation, reduced neuronal pyroptosis, and rescued memory following surgery.AAV-mediated knockdown of LCN2 in aged mice limited microglial inflammation, reduced neuronal pyroptosis, and rescued memory following surgery.

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