Sensory disorder

1 paper

Trial sponsors

IRCCS Sacro Cuore Don Calabria di Negrar
1 trial22 people

Funding

1 grant since 2023

National Institute on Deafness and Other Communication DisordersUS$588.2k

Mentoring Patient Oriented Research in sensory disorders
National Institute on Deafness and Other Communication DisordersStanford UniversityUS$195.5k2023–2028

Latest

9 in 12 months

Aging Cell30 Sep

IGF-1 and SLC25A33 preserve cochlear blood barrier integrity in aged mice

Targeting this pathway curbs mitochondrial oxidative stress and pericyte activation to partially restore auditory function in mouse models.Targeting this pathway curbs mitochondrial oxidative stress and pericyte activation to partially restore auditory function in mouse models.

Experiments in miceIGF1

Research Square24 Sep

Hearing impairment is associated with impaired glymphatic function in middle- and older-aged adults: evidence from DTI-ALPS imaging

Preprint: cross-sectional study of 131 peopleBiomarkers

Frontiers in Aging Neuroscience16 Sep

Advances in the treatment of age-related hearing loss: from molecular mechanisms to targeted interventions

ReviewEar

Hearing Research30 Mar

Acute nicotine affects auditory brainstem responses in a frequency-, age-, and sex-dependent manner in mice

Experiments in miceInterventions

Free Radical Biology & Medicine19 Mar

GPX3 activates autophagy to protect cochlear spiral ganglion neurons from injury in age-related hearing loss

Experiments in miceAutophagy

Free Radical Biology & Medicine28 Feb

NRH attenuates age-related hearing loss by suppressing cochlear ferroptosis and cellular senescence via Sirt3 activation

Experiments in miceAge-related hearing loss

Frontiers in Human Neuroscience13 Feb

What are the virtual reality solutions for dual-task intervention to promote health in aging? A scoping review

Systematic review of studies in peopleInterventions

Advanced Science31 Jan

Gut-Metabolome-Proteome Interactions in Age-Related Hearing Loss: Insights from Fecal Microbiota Transplantation and Multi-Omics Analyses

Experiments in miceFecal microbiota transplantation

Hearing Research26 Jan

Pbx1 overexpression delays cochlear hair cells degeneration in an accelerated aging mouse model

Experiments in miceEar

Neuroscience17 Oct

LCN2 promotes HEI-OC1 cells senescence via activating NF-κB signal pathway in presbycusis

Experiments in miceCellular senescence