AAV-PBX1

Intervention

1 paper2 findings

  • 1 lab in 1 country
  • Funders: National Natural Science Foundation of China and 1 more
  • Animals1

Outcomes

2

Auditory function

upin mice1

1 study
  1. AAV-PBX1 improves auditory function in mice.

    “in vivo delivery of Pbx1 by AAV improved auditory function and preserved HC structure and function in ARHL mouse model”

    Animalsin ARHL mouse model

    Pbx1 overexpression delays cochlear hair cells degeneration in an accelerated aging mouse model

    Hearing research20 Jan 2026

Cellular senescence

downin mouse cells1

1 study
  1. AAV-PBX1 decreases cellular senescence in mouse cells.

    “Pbx1 overexpression significantly suppresses senescent markers and preserves HC integrity”

    Cellsin D-galactose/LPS-induced aging models

    Pbx1 overexpression delays cochlear hair cells degeneration in an accelerated aging mouse model

    Hearing research20 Jan 2026

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