Senescent markers

Biomarker

2 papers

  • Humans1
  • Animals1

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Aging Cell

Time-restricted eating slows blood vessel aging in animals

In an animal experiment, limiting daily eating hours altered gut bacteria and boosted acetic acid, easing high blood pressure and artery stiffness.In an animal experiment, limiting daily eating hours altered gut bacteria and boosted acetic acid, easing high blood pressure and artery stiffness.

Experiments in animalsDietary restriction
Antioxidants & Redox Signaling

Protein loss caused senescence-like changes in lab-grown neurons

Experiments in models of neurons that regulate energy balance found cell enlargement and other senescence-like changes after researchers removed or reduced selenoprotein…Experiments in models of neurons that regulate energy balance found cell enlargement and other senescence-like changes after researchers removed or reduced selenoprotein T.

Experiments in miceCellular senescence
Nano Research

Scaffold and metformin sped new bone formation in aged mice

A bone-supporting scaffold plus metformin accelerated new bone formation in aged mice, most clearly when bone-forming cells lacked a protein involved in energy…A bone-supporting scaffold plus metformin accelerated new bone formation in aged mice, most clearly when bone-forming cells lacked a protein involved in energy metabolism.

Experiments in miceMetformin
Frontiers in Pharmacology

Melissic acid reduces senescence in human stem cells via cAMP signaling

A screen of 800 natural compounds identified a phytochemical that activates autophagy and restores cell-cycle activity in models of cellular exhaustion.A screen of 800 natural compounds identified a phytochemical that activates autophagy and restores cell-cycle activity in models of cellular exhaustion.

Experiments in human cellsInterventions