3 papers
University of Alabama at Birmingham
1 trialPhase 4100 people
National Institute of Diabetes and Digestive and Kidney Diseases
1 trialPhase 244 people
National Institute on AgingUS$5.2m
An observational analysis of 2,609 apparently healthy people linked the balance of two memory immune-cell groups to healthy and disease-associated aging patterns.An observational analysis of 2,609 apparently healthy people linked the balance of two memory immune-cell groups to healthy and disease-associated aging patterns.
A three-region model scored 0.81 versus 0.79 for a whole-brain model on a measure of how well it ranked death risk.A three-region model scored 0.81 versus 0.79 for a whole-brain model on a measure of how well it ranked death risk.
One lung immune cell population increased more than 10-fold in old mice compared with younger mice.One lung immune cell population increased more than 10-fold in old mice compared with younger mice.
In a PolgA-mutant mouse model, gut microbiota reduced systemic mitochondrial function while driving energy-demanding immune remodeling and protein synthesis through mTOR…In a PolgA-mutant mouse model, gut microbiota reduced systemic mitochondrial function while driving energy-demanding immune remodeling and protein synthesis through mTOR signaling.