Hepatic ischemia reperfusion injury

1. Fisetin protects against hepatic ischemia reperfusion injury in mice.

   “fisetin pretreatment reduced pathological liver damage, serum aminotransferase levels, serum concentrations of IL-1β, IL-18 and TNF-α in the murine IRI model.”

   Animalsin warm hepatic ischemia-reperfusion injuryliver5, 10 or 20 mg/kg

   Fisetin mitigates hepatic ischemia-reperfusion injury by regulating GSK3β/AMPK/NLRP3 inflammasome pathway

   Hepatobiliary & pancreatic diseases international : HBPD INT·8 May 2021

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1. Hydrogen sulfide protects against hepatic ischemia reperfusion injury in mice.

   “resulting in increased hydrogen sulfide (H2S) production and protection from hepatic ischemia reperfusion injury”

   Animalsin a mouse model of DR-mediated stress resistanceliver

   Endogenous hydrogen sulfide production is essential for dietary restriction benefits

   Cell·23 Dec 2014

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