FERROSTATIN-1
Intervention2 papers2 findingsPubChem 4068248ChEBI 173086
- Animals1
- Model organisms1
Outcomes
2Efferocytosis
upin human cells1
1 study
Efferocytosis
upin human cells1
FERROSTATIN-1 improves efferocytosis in human cells.
Cellsunder FIN-56 treatmentTHP-1-derived macrophages
Rapamycin reduces ferroptotic stress and shrinks atherosclerotic plaques in mice · International immunopharmacology · 2 Oct 2026
Lifespan
downin flies1
1 study
Lifespan
downin flies1
FERROSTATIN-1 protects against lifespan in flies.
Model organismsduring erastin and RSL3 treatment
Fruit flies provide an in vivo model to study ferroptosis and lifespan · Redox biology · 28 Sep 2026
Latest
2Rapamycin reduces ferroptotic stress and shrinks atherosclerotic plaques in mice
The mTOR inhibitor restored macrophage efferocytosis and mitochondrial function while lowering aortic lipid burden in high-fat-fed ApoE-deficient mice.
Fruit flies provide an in vivo model to study ferroptosis and lifespan
Ferroptosis-inducing compounds shortened fly lifespan in a diet-dependent manner, while antioxidant treatment restored longevity and reversed iron-related changes in males.