AAV8-SIRT3

AAV8-SIRT3 has been studied in 1 paper since 2026: none in people yet, 1 in animals; 1 in the past year. The research so far is in animals. The newest story, Nov 13, 2026: “Raising an immune-cell protein eased liver injury in aged mice”.

Intervention

1 paper studies it1 findingUpdated

1 new paper in 30 daysSee all 1 papers on AAV8-SIRT3

At a glance

The findings reach mice, none yet in people. 1 lab in 1 country.

Mice: a single group. Cells, worms or flies and humans: nothing yet.
  • 1 lab in 1 country
  • Animals1

What did studies of AAV8-SIRT3 find?

1

Studies of AAV8-SIRT3 measured one outcome, hepatic ischemia reperfusion injury.

Hepatic ischemia reperfusion injury

downin mice1

1 study
  1. AAV8-SIRT3 decreases hepatic ischemia reperfusion injury in mice (murine HIRI model).

    “SIRT3 overexpression in liver macrophages also alleviated HIRI of aged mice.”

    Animalsmurine HIRI modeladeno-associated virus serotype 8liver macrophage

    Raising an immune-cell protein eased liver injury in aged mice

    Hepatobiliary & pancreatic diseases international : HBPD INT

More on Hepatic ischemia reperfusion injury

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Hepatobiliary & Pancreatic Diseases International

Raising an immune-cell protein eased liver injury in aged mice

In experiments, aged mice had less of the protein and more injury than young mice after liver blood supply was interrupted and restored.In experiments, aged mice had less of the protein and more injury than young mice after liver blood supply was interrupted and restored.