clk-1

1. clk-1 improves oxygen consumption rate in worms.

   “co-knockdown of psd-1 along with the ETC component clk-1 rescued physiological defects such as restoring the lifespan of from 13.48 ± 0.51 days psd-1 RNAi worms to 17.36 ± 0.44 days in psd-1 ; clk-1 double-knockdown worms and normalizing oxygen consumption rate”

   Model organismsin psd-1 RNAi worms

   Suppressing clk-1 restores lifespan and mitochondrial function in psd-1 deficient worms · Antioxidants (Basel, Switzerland) · 20 Sep 2026

Oxygen consumption rate →

1. clk-1 extends lifespan in worms (from 13.48 ± 0.51 days to 17.36 ± 0.44 days).

   “co-knockdown of psd-1 along with the ETC component clk-1 rescued physiological defects such as restoring the lifespan of from 13.48 ± 0.51 days psd-1 RNAi worms to 17.36 ± 0.44 days”

   Model organismsin psd-1 RNAi worms

   Suppressing clk-1 restores lifespan and mitochondrial function in psd-1 deficient worms · Antioxidants (Basel, Switzerland) · 20 Sep 2026