Neuronal loss

Biomarker

2 papers1 finding

Animals2

Upstream

OPA1

downin mice1

1 study

OPA1 decreases neuronal loss in mice.
“Neuronal-specific OPA1 knockout in aged mice with distal middle cerebral artery occlusion (dMCAO) notably worsened mitochondrial cristae disruption, enlarged infarct volumes, and increased neuronal loss.”
Animalsdistal middle cerebral artery occlusion (dMCAO)brain
Decreased OPA1 expression increases neuronal vulnerability to ischaemic stroke during ageing: Role of Timm8b as a therapeutic target
Free radical biology & medicine8 Dec 2025

Latest

50 in 12 months

Physiology & Behavior9 Oct

Intermittent Fasting as a Therapeutic Strategy in Alzheimer's Disease: Understanding of Brain-Derived Neurotrophic Factor Modulation

ReviewIntermittent fasting

Paper

bioRxiv2 Oct

Sympathetic nerve aging in mouse skin is sexually dimorphic and reversible

Male mice experience greater distal axon withdrawal that can be reversed by targeting muscle niches with nerve growth factor.Male mice experience greater distal axon withdrawal that can be reversed by targeting muscle niches with nerve growth factor.

Preprint: experiments in miceSkin

Paper

Neural Regeneration Research2 Oct