ImAge

Biomarker

1 paper3 findings

Interventions

3

Chemotherapy

upin reviews1

1 study
  1. Chemotherapy increases ImAge.

    “increases after treatments like chemotherapy”

    Review

    Measuring Single-Cell Aging with an Imaging-based Biomarker of Chromatin and Epigenetic Aging

    Journal of visualized experiments : JoVE30 Jan 2026

More on Chemotherapy

Oskm reprogramming

downin reviews1

1 study
  1. Oskm reprogramming decreases ImAge.

    “significant decreases following rejuvenation strategies (such as caloric restriction and partial reprogramming through transient Oct4, Sox2, Klf4, and Myc (OSKM) expression)”

    Review

    Measuring Single-Cell Aging with an Imaging-based Biomarker of Chromatin and Epigenetic Aging

    Journal of visualized experiments : JoVE30 Jan 2026

More on Oskm reprogramming

Caloric restriction

downin reviews1

1 study
  1. Caloric restriction decreases ImAge.

    “showing sensitivity through significant decreases following rejuvenation strategies (such as caloric restriction”

    Review

    Measuring Single-Cell Aging with an Imaging-based Biomarker of Chromatin and Epigenetic Aging

    Journal of visualized experiments : JoVE30 Jan 2026

More on Caloric restriction

Latest

Nov 2025: 142Dec 2025: 466Jan 2026: 179Feb 2026: 59Mar 2026: 75Apr 2026: 2May 2026: 5Jun 2026: 15Jul 2026: 58Aug 2026: 409Sep 2026: 347Oct 2026: 1131,870 in 12 months
Acta Neuropathologica

Human brain vessels show distinct states in small vessel disease

Researchers identified three vessel states across disease severity by analysing 11,409 vessel fragments from post-mortem brain tissue from 20 cases.Researchers identified three vessel states across disease severity by analysing 11,409 vessel fragments from post-mortem brain tissue from 20 cases.

Cross-sectional study of 20 peopleMechanisms
European Radiology

Silent spinal fractures were common in UK Biobank adults

Scans identified moderate or severe spinal fractures in 14.6% of 2,446 symptom-free UK Biobank participants aged 40–79, including people with normal bone density.Scans identified moderate or severe spinal fractures in 14.6% of 2,446 symptom-free UK Biobank participants aged 40–79, including people with normal bone density.

Cross-sectional study of 2,446 peopleBones and joints
medRxiv

Heart shape scores improved prediction of a heart rhythm disorder

In people with preserved heart pumping, adding scores to standard measurements improved the concordance index, a measure of predictive accuracy, by 0.068.In people with preserved heart pumping, adding scores to standard measurements improved the concordance index, a measure of predictive accuracy, by 0.068.

Preprint: cohort study of 52,365 peopleBiomarkers
medRxiv

Heart scans yield reference ranges by age and sex

An observational analysis of 9,088 heart scans produced reference ranges for how heart muscle changes shape, with larger differences by age and sex than ethnicity.An observational analysis of 9,088 heart scans produced reference ranges for how heart muscle changes shape, with larger differences by age and sex than ethnicity.

Preprint: cohort study of 45,000 peopleBiomarkers
bioRxiv

Brain scan changes linked to vessel disease in squirrel monkeys

An animal experiment compared scans with brain tissue in young and older squirrel monkeys, linking an imaging measure to amyloid vessel disease and tissue injury.An animal experiment compared scans with brain tissue in young and older squirrel monkeys, linking an imaging measure to amyloid vessel disease and tissue injury.

Preprint: experiments in animalsBiomarkers