Mouse experiments found that suppressing senescence in tissue surrounding developing teeth delayed eruption, supporting its role in normal development.Mouse experiments found that suppressing senescence in tissue surrounding developing teeth delayed eruption, supporting its role in normal development.
In a mouse model of osteoporosis caused by ovary removal, bone-targeted engineered vesicles preserved bone structure and reduced bone-breakdown activity without causing…In a mouse model of osteoporosis caused by ovary removal, bone-targeted engineered vesicles preserved bone structure and reduced bone-breakdown activity without causing systemic toxicity.
Mice engineered to lack a protein developed abnormal kidney-filter deposits, but the loss did not severely impair kidney function.Mice engineered to lack a protein developed abnormal kidney-filter deposits, but the loss did not severely impair kidney function.
Experiments in mouse melanoma models found that dietary restriction suppressed tumor growth through effects that depended on the immune system.Experiments in mouse melanoma models found that dietary restriction suppressed tumor growth through effects that depended on the immune system.
Aged mice given an inhibitor of immune signaling starting four weeks before nerve injury showed better nerve fiber regrowth and rebuilding of insulation.Aged mice given an inhibitor of immune signaling starting four weeks before nerve injury showed better nerve fiber regrowth and rebuilding of insulation.
In an experiment in mice with ovaries removed, targeted particles restored spongy bone structure and bone strength.In an experiment in mice with ovaries removed, targeted particles restored spongy bone structure and bone strength.
In a cohort of 137 mother–offspring pairs, links between prenatal inflammation and cognitive performance at ages 57–62 differed by pregnancy stage.In a cohort of 137 mother–offspring pairs, links between prenatal inflammation and cognitive performance at ages 57–62 differed by pregnancy stage.
Who was studied137 mother-offspring dyads, approximately six decades
What changedHigher first-trimester inflammation was linked to better midlife thinking skills; higher second-trimester inflammation was linked to worse skills
The catchPregnancy stress and obesity were unaccounted for and could affect cognition independently of inflammation
![Overview of the episodic memory test of pattern completion and the magnetic resonance imaging (MRI) sequences (Figure modified from Nyberg et al. [22]).](/_next/image?url=%2Ffig%2FMED-42927106%2F50261522.webp&w=1600&q=75&dpl=c055b560e5e1)
