Acetylation

1 paper

Animals1

Funding

7 grants since 2022

National Heart, Lung, and Blood InstituteUS$853.4kNational Institute of Neurological Disorders and StrokeUS$782.4kWellcome Trust£471.4k

The role of microtubule acetylation in SASP modulation
Wellcome TrustQueen Mary University of London£471.4k2024–2027
Alcohol-induced changes in protein acetylation: mechanisms and consequences
National Institute on Alcohol Abuse and AlcoholismCatholic University of AmericaUS$277.7k2009–2027
Investigating the novel role of acetylation in cardiac mitochondrial bioenergetics and function in the aging heart
National Heart, Lung, and Blood InstituteWest Virginia UniversityUS$248.8k2020–2024
Reversible protein acetylation and sirtuin function
National Institute of General Medical SciencesUniversity of Wisconsin-madisonUS$449.7k2003–2023
Acetylation and contraction-mediated glucose uptake
National Institute on AgingUniversity of California, San DiegoUS$202.6k2021–2024
TDP-43 acetylation, phase separation, aggregation, and clearance by antibody-mediated degradation
National Institute of Neurological Disorders and StrokeUniversity of California, San DiegoUS$782.4k2021–2026
Sirtuin 3 Inactivation and SOD2 Acetylation in Vascular Dysfunction and Hypertension
National Heart, Lung, and Blood InstituteVanderbilt University Medical CenterUS$604.6k2021–2025

Latest

187 in 12 months

Journal of the American Heart AssociationYesterday

Combined Associations of Glycoprotein Acetylation With Lipoprotein (a) and hs-CRP (High-Sensitivity C-Reactive Protein) on Risk of Cardiovascular Disease in MESA

Cohort study of 6,676 peopleLipoprotein

Paper

International Journal of Molecular SciencesYesterday

Removing a protein reduced lung tumour burden in mice

An animal experiment found that mice lacking the protein PA200 had reduced chemically induced lung tumour burden, especially in middle age.An animal experiment found that mice lacking the protein PA200 had reduced chemically induced lung tumour burden, especially in middle age.

Mouse studyLung

Paper

Clinical NutritionYesterday

Lysine breakdown linked to limb lean mass in humans

In 40 postmenopausal women, blood and muscle measurements suggested distinct changes rather than a uniform shift across the lysine breakdown pathway.In 40 postmenopausal women, blood and muscle measurements suggested distinct changes rather than a uniform shift across the lysine breakdown pathway.

Mendelian randomizationMechanisms

Paper

Scientific ReportsOct 15

Composite inflammatory indices and incident lung cancer risk in an exploratory statistical mediation analysis

Cohort study of 416,656 peopleLung cancer

Paper

Zhongguo Zhong Yao Za ZhiOct 14

Effects and mechanisms of Supplemented Shenqi Dihuang Decoction Formula improving renal aging and tubulointerstitial fibrosis in diabetic kidney disease by inhibiting ferroptosis

Experiments in ratsSGLT2 inhibitors

Paper

The FEBS JournalOct 13

Caloric restriction alters early renal responses to reversible obstructive nephropathy in rats

Experiments in ratsDietary restriction

Paper

eLifeOct 8

Periodic red light exposure eases cellular aging in mice

In aged mice, periodic red light exposure raised histone acetylation across tissues and reduced SIRT4 levels in skin cells to activate lipid metabolism.In aged mice, periodic red light exposure raised histone acetylation across tissues and reduced SIRT4 levels in skin cells to activate lipid metabolism.

Experiments in miceInterventions

Paper

Aging CellOct 8

Time-restricted eating slows blood vessel aging in animals

In an animal experiment, limiting daily eating hours altered gut bacteria and boosted acetic acid, easing high blood pressure and artery stiffness.In an animal experiment, limiting daily eating hours altered gut bacteria and boosted acetic acid, easing high blood pressure and artery stiffness.

Experiments in animalsDietary restriction

Paper

Journal of Biochemical and Molecular ToxicologyOct 7

Diesel-derived chemical triggers scarring signals in kidney cells

Experiments in kidney cells grown in the lab found that a diesel exhaust breakdown product caused lasting DNA damage and signals that activated connective-tissue cells.Experiments in kidney cells grown in the lab found that a diesel exhaust breakdown product caused lasting DNA damage and signals that activated connective-tissue cells.

Experiments in cellsKidney

Paper

Aging CellOct 7

Acetate reduced flu virus multiplication in human lung cells

In human lung cells that had stopped dividing, laboratory experiments found that acetate also reduced inflammatory responses.In human lung cells that had stopped dividing, laboratory experiments found that acetate also reduced inflammatory responses.

Experiments in human cellsLung

Paper

Acetylation

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