Puerarin
Intervention1 paper2 findingsPubChem 5281807ChEBI 8633
- Animals1
Outcomes
2Histone modification and chromatin remodelling
upin mouse cells1Very low certainty
1 study
Histone modification and chromatin remodelling
upin mouse cells1Very low certainty
Puerarin increases histone modification and chromatin remodelling in mouse cells.
“ZIF-90@PU treatment was associated with increased H3K18 lactylation and reduced NFATc1 signaling”
Cells
Puerarin-loaded nanoparticles improve bone mass in mice · Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 27 Sep 2026
Bone strength
upin mice1Very low certainty
1 study
Bone strength
upin mice1Very low certainty
Puerarin improves bone strength in mice.
“Administration of ZIF-90@PU to ovariectomized (OVX) mice produced significant gains in bone mineral density, trabecular architecture, and bone strength without detectable toxicity.”
Animalsin ovariectomized mice
Puerarin-loaded nanoparticles improve bone mass in mice · Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 27 Sep 2026
Latest
1Puerarin-loaded nanoparticles improve bone mass in mice
In ovariectomized mice, six weeks of treatment with pH-responsive puerarin nanoparticles restored trabecular bone architecture and increased bone…In ovariectomized mice, six weeks of treatment with pH-responsive puerarin nanoparticles restored trabecular bone architecture and increased bone mineral density.