HMGA1

Gene4 papers2 findingsHGNC 5010NCBI Gene 3159Taxon 9606

Animals2
Cells2

Effects

1

Cellular senescence

downin mouse cells1

1 study

HMGA1 inhibits cellular senescence in mouse cells.
Cellsin HGPS cells
HMGA1-HP1β axis regulates premature aging in Hutchinson-Gilford progeria syndrome through chromatin remodeling · Nature communications · 19 Aug 2026

Cellular senescence →

Upstream

1

DHX36

downin mouse cells1

1 study

DHX36 decreases HMGA1 in mouse cells.
Cellsneurons
Stress-induced helicase DHX36 controls neuroinflammation · The Journal of biological chemistry · 22 Sep 2026

Latest

4

The Journal of Biological ChemistryCells22 Sep

Stress-induced helicase DHX36 controls neuroinflammation

bioRxivCellsPreprint21 Sep

Single-cell multiomic QTL mapping reveals state-dependent genetic regulation and associated gene during cellular senescence

Cellular senescence

Nature CommunicationsAnimals17 Sep

HMGA1-HP1β axis regulates premature aging in Hutchinson-Gilford progeria syndrome through chromatin remodeling

Research SquareAnimalsPreprint22 Aug

CIP2A promotes osteoclastogenesis and postmenopausal bone loss by activating a novel HMGA1–c-Myc–PI3K/AKT axis

PI3K–AKT signalling