DHX36
Gene1 paper6 findingsHGNC 14410NCBI Gene 170506Taxon 9606
In a study spanning cells, mice and humans, DHX36 inhibits neuronal inflammation and lowers HMGA1 and HMGA2 in mouse neurons; pyridostatin lowers DHX36 in mouse cortical neurons. The study also links DHX36 to aged brains in mice and humans.
- Cells1
Interventions
1Pyridostatin
downin mouse cells1Very low certainty
1 study
Pyridostatin
downin mouse cells1Very low certainty
Pyridostatin decreases DHX36 in mouse cells.
Cellscortical neurons
Stress-induced helicase DHX36 controls neuroinflammation · The Journal of biological chemistry · 22 Sep 2026
Effects
3HMGA2
downin mouse cells1
1 study
HMGA2
downin mouse cells1
DHX36 decreases HMGA2 in mouse cells.
Cellsneurons
Stress-induced helicase DHX36 controls neuroinflammation · The Journal of biological chemistry · 22 Sep 2026
HMGA1
downin mouse cells1
1 study
HMGA1
downin mouse cells1
DHX36 decreases HMGA1 in mouse cells.
Cellsneurons
Stress-induced helicase DHX36 controls neuroinflammation · The Journal of biological chemistry · 22 Sep 2026
Inflammation
downin cells1
1 study
Inflammation
downin cells1
DHX36 inhibits inflammation in cells.
Cellsneurons
Stress-induced helicase DHX36 controls neuroinflammation · The Journal of biological chemistry · 22 Sep 2026
Associations
1Aged brain
upin humans1upin mice1
1 study
Aged brain
upin humans1upin mice1
Aged brain is associated with DHX36 in humans.
Humansbrain
Stress-induced helicase DHX36 controls neuroinflammation · The Journal of biological chemistry · 22 Sep 2026
Aged brain is associated with DHX36 in mice.
Animalsbrain
Stress-induced helicase DHX36 controls neuroinflammation · The Journal of biological chemistry · 22 Sep 2026