BAZ1B

2 papers1 finding

HGNC MGI NCBI Gene Taxon

1 lab in 1 country

Funders: Basic and Applied Basic Research Foundation of Guangdong Province and 6 more

Humans2

Effects

1

Unexplained miscarriage

downin mice1

1 study

BAZ1B protects against unexplained miscarriage in mice.
“Therapeutic down-regulation of p21, supplement with murine Baz1b, or direct suppression of senescence could effectively reduce placental senescence and suppress mouse miscarriage in the 6PPD-exposed mouse models.”
Animalsin 6PPD-exposed mouse models
Exposure to high doses of tyre antioxidant 6PPD causes senescence to induce unexplained miscarriage by suppressing BAZ1B-mediated ubiquitination degradation of P21
EBioMedicine1 Jun 2026

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