Vascular senescence

Disease

1 paper

  • Animals1

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Journal of Cellular Biochemistry

Chronic stress worsened bone loss in mice after ovary removal

In an animal experiment, mice whose ovaries had been removed showed worse osteoporosis and anxiety- and depression-like behaviour after eight weeks of chronic stress.In an animal experiment, mice whose ovaries had been removed showed worse osteoporosis and anxiety- and depression-like behaviour after eight weeks of chronic stress.

Experiments in miceBones and joints
bioRxiv

Lactate receptor activation reduces arterial senescence in mice

In progeroid mice, activating the GPR81 receptor with the agonist CHBA reduced arterial lipid buildup, lowered cellular senescence, and improved endothelial integrity.In progeroid mice, activating the GPR81 receptor with the agonist CHBA reduced arterial lipid buildup, lowered cellular senescence, and improved endothelial integrity.

Preprint: experiments in miceInterventions