Cardiac diastolic dysfunction

4 papers2 findings

Animals4

Interventions

2

Empagliflozin

downin mice1

1 study

Empagliflozin decreases cardiac diastolic dysfunction in mice.
“EMPA administration effectively ameliorated metabolic disorders and cardiac diastolic dysfunction in HFD-fed mice.”
Animalsin HFD-fed mice8 weeksmales
Empagliflozin alleviates obesity-related cardiac dysfunction via the activation of SIRT3-mediated autophagosome formation
Lipids in health and diseaseSep 27, 2024

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Epigallocatechin gallate

downin mice1

1 study

Epigallocatechin gallate prevents cardiac diastolic dysfunction in mice.
“Long-term administration of 100 or 200 mg EGCG prevented aging-related CDD”
Animalsmixed with drinking waterheart100 or 200 mg6 monthsfemales
The effect of long-term administration of green tea catechins on aging-related cardiac diastolic dysfunction and decline of troponin I
Genes & diseasesApr 3, 2024

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Latest

3 in 12 months

Frontiers in Cardiovascular MedicineOct 9

Vessel lining damage linked to heart dysfunction in Chinese adults

In 503 retired adults in China, each 0.1-micrometre rise in a marker of vessel lining damage was linked to 12% higher odds of asymptomatic heart dysfunction.In 503 retired adults in China, each 0.1-micrometre rise in a marker of vessel lining damage was linked to 12% higher odds of asymptomatic heart dysfunction.

Cohort study of 503 peopleBiomarkers

British Journal of PharmacologySep 11

GPER stimulation attenuates mitochondrial dysfunction and cardiac dysfunction in ovariectomized mice with heart failure with preserved ejection fraction (HFpEF)

Experiments in miceHeart failure with preserved ejection fraction

Experimental GerontologyAug 24

Peripheral blood mitochondrial DNA copy number is associated with cardiac diastolic dysfunction in frail older adults

Cohort study of 187 peopleMitochondrial DNA copy number

Genes & DiseasesJan 6

The effect of long-term administration of green tea catechins on aging-related cardiac diastolic dysfunction and decline of troponin I

Experiments in miceInterventions

GSA 2024 AbstractJan 1

GLYNAC AND THE AGING MOUSE HEART: SEX-RELATED DIFFERENCES AND OUTCOMES

Experiments in miceInterventions

Lipids in Health and DiseaseSep 27

Empagliflozin alleviates obesity-related cardiac dysfunction via the activation of SIRT3-mediated autophagosome formation

Experiments in miceEmpagliflozin

FASEB JournalJul 24

Cardiac diastolic dysfunction by cigarette smoking is associated with mitochondrial integrity in the heart

Study in peopleOxidative phosphorylation

GeroScienceJul 8

Klotho enhances diastolic function in aged hearts through Sirt1-mediated pathways

Experiments in miceInterventions

Scientific ReportsApr 4

Aerobic exercise attenuates dysautonomia, cardiac diastolic dysfunctions, and hemodynamic overload in female mice with atherosclerosis

Experiments in 18 miceAerobic exercise

Aging CellDec 15

MiR-203 improves cardiac dysfunction by targeting PARP1-NAD⁺ axis in aging murine

Experiments in miceInterventions