GLYNAC AND THE AGING MOUSE HEART: SEX-RELATED DIFFERENCES AND OUTCOMES
GSA 2024 Abstract
Abstract
Aging is associated with increased reactive oxygen species (ROS) resulting from an imbalance in antioxidant defenses and a rise in proinflammatory milieu. Glutathione (GSH) is a naturally occurring antioxidant which concentration is reduced in aging.
- Glynac
- Extracellular matrix remodelling
- Fatty acid β-oxidation
- Diastolic dysfunction
- Cardiac diastolic function
- Mice
