Carcinogenesis

Disease

3 papers3 findings

  • Animals1

Interventions

1

Resveratrol

downin reviews1

1 study
  1. Resveratrol inhibits carcinogenesis.

    “this stilbene blocks the multistep process of carcinogenesis at various stages: tumor initiation, promotion, and progression.”

    Review

    Resveratrol as an anti-inflammatory and anti-aging agent: mechanisms and clinical implications

    Molecular nutrition & food research1 May 2005

More on Resveratrol

Associations

2

NF-κB signalling

upin reviews1

1 study
  1. NF-κB signalling is associated with carcinogenesis.

    “Thus, there is evidence of the participation of NF-κB in the processes of aging, carcinogenesis, regulation of proliferation, and apoptosis.”

    Review

    Biological significance of the NF-κb mechanism in aging

    Advances in gerontology = Uspekhi gerontologii1 Jan 2025

More on NF-κB signalling

Critically shortened telomeres

upin reviews1

1 study
  1. Critically shortened telomeres raise the risk of carcinogenesis.

    “critically shortened telomeres may promote chromosomal instability. These changes can lead to the development of carcinogenesis.”

    Review

    Maintaining telomere length

    Postepy higieny i medycyny doswiadczalnej (Online)17 Dec 2013

More on Critically shortened telomeres

Funding

16 grants since 2022

National Cancer InstituteUS$8.2mVeterans AffairsNIH Office of the DirectorUS$1.5m

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medRxiv

Multimorbidity units link to steeper disease incidence with age

In 502,355 UK Biobank participants, diagnoses tied to more functional disease units showed steeper rises in incidence with age (Spearman rho = 0.50).In 502,355 UK Biobank participants, diagnoses tied to more functional disease units showed steeper rises in incidence with age (Spearman rho = 0.50).

Preprint: cohort study of 502,355 peopleMechanisms