Cervical cancer

1. Smoking has no effect on cervical cancer in humans.

   HumansEast Asian populations

   Epidemiological characteristics of cervical cancer in Asian populations and risk factor inference based on Mendelian randomization · Medicine · 2 Oct 2026

Smoking →

1. Hpv vaccine lowers the risk of cervical cancer in silico (1.82 million cases averted (53% reduction)).

   “Continuation of Nigeria's current adolescent program is projected to avert 1.82 million cervical cancer cases (IQR 1.65-1.90 million; 95% UI 1.39-2.02 million) over 2025-2100 (a 53% reduction relative to no vaccination”

   In silico2025-2100

   Model-based evaluation of an infant HPV prophylactic vaccination program in Nigeria · medRxiv · 2 Oct 2026 · Preprint

2. Hpv vaccine lowers the risk of cervical cancer in humans.

   Reviewfemales

   Human Papillomavirus (HPV) and Cervical Cancer: An Exploratory Systematic Review of Heterogeneous Evidence on Epidemiology, Vaccination, Screening, and Molecular Advances · Cancer investigation · 29 Sep 2026

Hpv vaccine →

1. Cervical cancer screening lowers the risk of cervical cancer in silico (~387K cases averted).

   “Scaling up screening to WHO targets was estimated to avert a further ~387K cases (IQR 331-424K; 95% UI 269-515K), roughly 25% of the residual burden”

   In silicoWHO targets scale-up (70% aggregate)2025-2100

   Model-based evaluation of an infant HPV prophylactic vaccination program in Nigeria · medRxiv · 2 Oct 2026 · Preprint

Cervical cancer screening →

1. Older age raises the risk of cervical cancer in humans (aRR 5.02, 95% CI 2.43-10.35).

   Humanscompared with participants aged <45 years

   From HPV genotypes to cervical lesion burden: public health-relevant heterogeneity across 1.29 million screening records in Guangdong, China · Frontiers in public health · 17 Sep 2026

1. Human papillomavirus infection raises the risk of cervical cancer in humans (AAPC 5.89% (95% CI: 2.82-9.06)).

   Humansfemales

   Geographic and temporal variations in cancer incidence attributable to human papillomavirus infection in China: a population-based study · BMC public health · 8 Sep 2026

Human papillomavirus infection →