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medRxivHumansPreprint

PTSD is linked to accelerated DNA methylation aging

In a preprint analyzing epigenome-wide data from thousands of U.S. veterans, posttraumatic stress disorder was significantly associated with…In a preprint analyzing epigenome-wide data from thousands of U.S. veterans, posttraumatic stress disorder was significantly associated with accelerated DNA methylation aging.

GenesHumans

Blood methylation clocks capture two distinct biological domains of aging

Specific epigenetic measures track mitotic cell replication, while others capture systemic dysregulation driven by inflammation, metabolic factors…Specific epigenetic measures track mitotic cell replication, while others capture systemic dysregulation driven by inflammation, metabolic factors, and lifestyle exposures.