Research
A Military Veteran with Pulmonary Fibrosis, Hepatic Cirrhosis, Bone Marrow Dysfunction and Shortened Telomeres Found to Have GAVE, a Potential Unsuspected Consequence of Telomere Spectrum Disorder
Abstract · CC BY
Background: Telomeres are repetitive DNA sequences at chromosome ends that maintain genomic stability and shorten with age. Mutations in genes such as DKC1, TERC, TERT, NOP10, TINF2 and NHP2 cause Telomere Spectrum Disorders (TSD), leading to shortened telomeres.
- Gulf war oil fire pollutants
- Genomic instability
- Telomere attrition
- Oxidative stress and ROS signalling
- Telomerase and telomere maintenance
- Anemia
- Gastric antral vascular ectasia
- Idiopathic pulmonary fibrosis
- Liver cirrhosis
- Telomere spectrum disorder
- Thrombocytopenia
- Telomere length
The paper
A Military Veteran with Pulmonary Fibrosis, Hepatic Cirrhosis, Bone Marrow Dysfunction and Shortened Telomeres Found to Have GAVE, a Potential Unsuspected Consequence of Telomere Spectrum Disorder
Uhlen A, Oudit OA, Patel D et al.
Journal of Clinical Medicine · 11 Sep 2026