Mice with one working copy of the protein’s gene had enlarged, scarred hearts and poorer pumping, resembling changes in aged mice.Mice with one working copy of the protein’s gene had enlarged, scarred hearts and poorer pumping, resembling changes in aged mice.
Male mice carrying the same diabetes-linked mutation developed diabetes on a mixed genetic background, but maintained normal blood sugar on another background.Male mice carrying the same diabetes-linked mutation developed diabetes on a mixed genetic background, but maintained normal blood sugar on another background.
An analysis of adult human brain RNA data found age-linked patterns in the mix of RNA versions that persisted after accounting for each gene’s total RNA amount.An analysis of adult human brain RNA data found age-linked patterns in the mix of RNA versions that persisted after accounting for each gene’s total RNA amount.
Three weeks of protein injections reduced weight in male and female mice, with greater effects in older mice and those fed a high-fat diet.Three weeks of protein injections reduced weight in male and female mice, with greater effects in older mice and those fed a high-fat diet.
The method paired gene activity and DNA-marking measurements at about 10,000 cells per sequencing library, a collection of prepared genetic material.The method paired gene activity and DNA-marking measurements at about 10,000 cells per sequencing library, a collection of prepared genetic material.