Protein
Biomarker2 papers
- Humans1
Funding
Wellcome Trust£3.8mNIH Office of the DirectorUS$3.4mNational Cancer InstituteUS$773.8k4 grants since 2022
Alternative Mechanisms of Signaling via Trimeric G Proteins
National Institute of Neurological Disorders and StrokeBoston University Medical CampusUS$22k2026–2027
National Cancer InstituteLsu Health Sciences CenterUS$773.8k2022–2028
NIH Office of the DirectorMontana State University - BozemanUS$3.4m2026–2027
Disentangling the diverse forms of collective protein homeostasis in neuronal condensates
Wellcome TrustKing's College London£3.8m2026–2034
Latest
1,308Protein deficiency impaired memory in aging mice
Experiments in 15-month-old mice with reduced Nipsnap1, a protein involved in cell maintenance, found reduced gene activity linked to nerve-cell…Experiments in 15-month-old mice with reduced Nipsnap1, a protein involved in cell maintenance, found reduced gene activity linked to nerve-cell signalling and increased activity linked to inflammation.
Young-donor cell packages improved limb repair in rats
In a rat experiment, cell-released packages from young donors had stronger tissue-repair effects than those from older donors after blood supply was…In a rat experiment, cell-released packages from young donors had stronger tissue-repair effects than those from older donors after blood supply was restricted.
Probiotic shortened gut transit time in older adults
A randomised, double-blind trial also found changes in gut bacteria, including suppression of bacteria that produce an enzyme involved in processing…A randomised, double-blind trial also found changes in gut bacteria, including suppression of bacteria that produce an enzyme involved in processing bile acids.
Protein comparisons identify new longevity regulators in worms
Researchers compared five protein-measuring methods in worms with mutations in an insulin-related signalling system, then used genetic screening to…Researchers compared five protein-measuring methods in worms with mutations in an insulin-related signalling system, then used genetic screening to identify longevity regulators.
New protein form pushed lab-grown cells to stop dividing
Cell experiments identified a previously unknown protein form that responded to DNA damage and triggered senescence, a state in which cells stop…Cell experiments identified a previously unknown protein form that responded to DNA damage and triggered senescence, a state in which cells stop dividing.
Weight Loss or Muscle Loss? Cellular Mechanisms and Clinical Strategies for Preserving Lean Mass During GLP-1-Based Therapy
Boosting sugar breakdown increased bone mass in aged mice
Experiments linked reduced bone formation to impaired sugar breakdown, while genetic changes that enhanced the process improved bone-forming cell…Experiments linked reduced bone formation to impaired sugar breakdown, while genetic changes that enhanced the process improved bone-forming cell function in aged mice.
Tetanus vaccine ingredient improved learning and memory in aging mice
An experiment in twelve-month-old mice found better learning and memory alongside more immature nerve cells and greater insulation around nerve…An experiment in twelve-month-old mice found better learning and memory alongside more immature nerve cells and greater insulation around nerve fibres.
A protein helped egg cells from aged cattle mature in the lab
In laboratory experiments, injecting instructions for making a protein reduced maturation failure in aged cattle egg cells and restored the function…In laboratory experiments, injecting instructions for making a protein reduced maturation failure in aged cattle egg cells and restored the function of their energy-producing structures.