Short Physical Performance Battery

Biomarker12 papers7 findings

  • Human trial1
  • Humans9

Effects

2

Frailty discrimination

upin humans1

1 study
  1. Short Physical Performance Battery improves frailty discrimination in humans.

    Humansin patients with COPD and ILD awaiting lung transplantationn = 82

    Assessing frailty in lung transplantation candidates · medRxiv · 29 Sep 2026 · Preprint

Frailty discrimination →

Kidney failure

no changein humans1

1 study
  1. Short Physical Performance Battery has no effect on kidney failure in humans.

    Humansbaseline and time-updated, fully adjustedn = 3,038

    Physical performance links to heart failure and death in CKD · Clinical journal of the American Society of Nephrology : CJASN · 29 Sep 2026

Kidney failure →

Associations

5

Test-retest reliability

upin humans1

1 study
  1. Short Physical Performance Battery is associated with test-retest reliability in humans (ICC = 0.931; p ≤ 0.001).

    Human trialinstitutionalized adults with intellectual and developmental disabilitiesn = 32

    Testing the Reliability of the Short Physical Performance Battery in Institutionalized Individuals With Intellectual and Developmental Disabilities · Journal of intellectual disability research : JIDR · 1 Oct 2026

Heart failure

upin humans1

1 study
  1. Short Physical Performance Battery is associated with heart failure in humans (+10% per 1-point lower score).

    Humanstime-updated analyses, fully adjustedn = 3,038

    Physical performance links to heart failure and death in CKD · Clinical journal of the American Society of Nephrology : CJASN · 29 Sep 2026

Heart failure →

Mortality

upin humans1

1 study
  1. Short Physical Performance Battery is associated with mortality in humans (+14% per 1-point lower score).

    Humansfully adjustedn = 3,038

    Physical performance links to heart failure and death in CKD · Clinical journal of the American Society of Nephrology : CJASN · 29 Sep 2026

StaBLE score

upin humans1

1 study
  1. StaBLE score is associated with Short Physical Performance Battery in humans (τ = 0.57).

    Humansn = 180

    Video-derived balance score tracks age and fall risk · bioRxiv : the preprint server for biology · 23 Sep 2026 · Preprint

StaBLE score →

Frailty

downin humans1

1 study
  1. Short Physical Performance Battery is associated with frailty in humans.

    “poor nutritional status (lower MNA-SF score), impaired physical function (lower SPPB score), and reduced LVEF are important correlates of frailty severity in these patients.”

    Humanshospitalized patients with heart failure

    Prevalence and associated factors of frailty in hospitalized elderly patients with heart failure · Frontiers in cardiovascular medicine · 14 Sep 2026

Latest

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medRxivHuman trialPreprint

Blood proteins predict physical rehab gains in older adults

Baseline protein profiles stratified 12-week physical gains from rehabilitation over control, spanning 10 to 85 meters on the six-minute walk test.Baseline protein profiles stratified 12-week physical gains from rehabilitation over control, spanning 10 to 85 meters on the six-minute walk test.

bioRxivHumansPreprint

Video-derived balance score tracks age and fall risk

Tested in 180 participants, the StaBLE score correlated strongly with age (ρ = -0.76) and separated individuals at risk of falling from those who were…Tested in 180 participants, the StaBLE score correlated strongly with age (ρ = -0.76) and separated individuals at risk of falling from those who were not.

PLOS OneHuman trial

High-intensity walking improves frailty in older adults

Frailty category improved in 69.6% of high-intensity walkers compared with 46.4% of casual-speed walkers over a 16-week intervention.Frailty category improved in 69.6% of high-intensity walkers compared with 46.4% of casual-speed walkers over a 16-week intervention.

Nature CommunicationsHuman trial

Multidisciplinary care reduces frailty in older cardiac patients

In a randomized trial, the year-long RENAP regimen yielded an adjusted mean difference of -0.79 in frailty and 2.02 in physical performance against…In a randomized trial, the year-long RENAP regimen yielded an adjusted mean difference of -0.79 in frailty and 2.02 in physical performance against usual care.