Kidney failure

Disease4 papers4 findings

  • Humans4

Upstream

1

Short Physical Performance Battery

no changein humans1

1 study
  1. Short Physical Performance Battery has no effect on kidney failure in humans.

    Humansbaseline and time-updated, fully adjustedn = 3,038

    Physical performance links to heart failure and death in CKD · Clinical journal of the American Society of Nephrology : CJASN · 29 Sep 2026

Short Physical Performance Battery →

Associations

3

Methylation risk score

upin humans1

1 study
  1. Methylation risk score is associated with kidney failure in humans.

    Humansin HyperGEN and MESA

    Integrated Risk Prediction of Kidney Failure: Clinical and Multi-Omic Approaches · Clinical journal of the American Society of Nephrology : CJASN · 29 Sep 2026

Methylation risk score →

Polygenic risk score

upin humans1

1 study
  1. Polygenic risk score is associated with kidney failure in humans.

    Humansin HyperGEN

    Integrated Risk Prediction of Kidney Failure: Clinical and Multi-Omic Approaches · Clinical journal of the American Society of Nephrology : CJASN · 29 Sep 2026

Polygenic risk score →

Family history of chronic kidney disease

upin humans1OR 3.15

1 study
  1. family history of chronic kidney disease raises the risk of kidney failure in humans (pooled OR 3.15, 95% CI: 1.92, 5.22).

    Humans

    Prevalence and significance of family history of kidney disease in the electronic health record in three United States health systems · Kidney international · 28 Sep 2026

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Kidney MedicineHumans

Neighborhood disadvantage links to dementia in kidney failure

Among older dialysis patients, living in highly disadvantaged neighborhoods was linked to adjusted hazard ratios of 1.09 for dementia and 1.25 for…Among older dialysis patients, living in highly disadvantaged neighborhoods was linked to adjusted hazard ratios of 1.09 for dementia and 1.25 for Alzheimer's disease.

Clinical Journal of the American Society of NephrologyHumans

Physical performance links to heart failure and death in CKD

Among 3,038 adults with chronic kidney disease, each 1-point lower physical performance score was associated with a 10% higher heart failure risk and…Among 3,038 adults with chronic kidney disease, each 1-point lower physical performance score was associated with a 10% higher heart failure risk and 15% higher mortality.