Cerebral small vessel disease
Disease6 papers5 findingsMeSH D059345
- Humans4
- Animals1
Effects
2Gait performance
downin humans1
1 study
Gait performance
downin humans1
Cerebral small vessel disease impairs gait performance in humans.
Humanscompared with control participants
Gait performance in cerebral small vessel disease: associations with cognitive and oculomotor function and exploratory mediation analyses · Frontiers in aging neuroscience · 16 Sep 2026
Myocardial infarction
no changein humans1
1 study
Myocardial infarction
no changein humans1
Cerebral small vessel disease has no effect on myocardial infarction in humans.
Humansmedian follow-up of 8.4 yearsn = 3,263
Brain small vessel disease links to stroke and mortality risk · medRxiv : the preprint server for health sciences · 7 Sep 2026 · Preprint
Associations
3Stroke
upin humans1
1 study
Stroke
upin humans1
Cerebral small vessel disease raises the risk of stroke in humans.
Humansmedian follow-up of 8.4 yearsn = 3,263
Brain small vessel disease links to stroke and mortality risk · medRxiv : the preprint server for health sciences · 7 Sep 2026 · Preprint
Mortality
upin humans1
1 study
Mortality
upin humans1
Cerebral small vessel disease raises the risk of mortality in humans.
Humansmedian follow-up of 8.4 yearsn = 3,263
Brain small vessel disease links to stroke and mortality risk · medRxiv : the preprint server for health sciences · 7 Sep 2026 · Preprint
Composite cardiovascular events and mortality
upin humans1HR 1.48
1 study
Composite cardiovascular events and mortality
upin humans1HR 1.48
Cerebral small vessel disease raises the risk of composite cardiovascular events and mortality in humans (HR 1.48, 95% CI 1.19-1.85).
HumansCSVD score 1 vs 0median follow-up of 8.4 yearsn = 3,263
Brain small vessel disease links to stroke and mortality risk · medRxiv : the preprint server for health sciences · 7 Sep 2026 · Preprint
Latest
7Brain small vessel disease links to stroke and mortality risk
Compared with a zero score, participants with cerebral small vessel disease scores of 1 and 2 had hazard ratios of 1.48 and 1.52 for adverse events.Compared with a zero score, participants with cerebral small vessel disease scores of 1 and 2 had hazard ratios of 1.48 and 1.52 for adverse events.
Col4a2 mutation disrupts cerebral artery function in aged mice
In 12-month-old Col4a2 mutant mice, cerebral pial arteries showed impaired myogenic tone driven by PKA-dependent remodeling of ryanodine receptor…In 12-month-old Col4a2 mutant mice, cerebral pial arteries showed impaired myogenic tone driven by PKA-dependent remodeling of ryanodine receptor clusters.
Gait performance in cerebral small vessel disease: associations with cognitive and oculomotor function and exploratory mediation analyses
Optimal LDL-C Levels for Ischemic Stroke Prevention: A Neurologist's Perspective
White matter changes accelerate cortical thinning more in men
Across nine years in 104 older adults, white matter aberrations grew 7.2% annually, driving accelerated cortical thinning that was more pronounced in…Across nine years in 104 older adults, white matter aberrations grew 7.2% annually, driving accelerated cortical thinning that was more pronounced in men than women.