Blood flow restriction training
Intervention4 papers10 findings
A human trial in hospitalised older adults with sarcopenia shows blood flow restriction training improves Modified Barthel Index, physical performance, grip strength, gait speed and Timed Up-and-Go versus resistance training. A separate human trial reports increased lactate in men after 12 weeks.
- Human trial4
Outcomes
10Lactate
upin humans1Low certainty
1 study
Lactate
upin humans1Low certainty
Blood flow restriction training increases lactate in humans.
Human trial12 weeksmales
Comparing high-intensity resistance training incorporating periodic eccentric-only exercise with blood flow restriction training in older men: physiological responses and exercise feasibility · European journal of applied physiology · 24 Sep 2026
Health-related quality of life
upin humans1Low certainty
1 study
Health-related quality of life
upin humans1Low certainty
Blood flow restriction training improves health-related quality of life in humans (p-value <0.001).
Human trialend-stage chronic kidney disease on hemodialysis8 weeksn = 36
Effect of Intradialytic Blood Flow Restriction Training on Functional Capacity, Estimated Glomerular Filtration Rate and Health-Related Quality of Life in Patients on Hemodialysis: A Randomized Controlled Trial · Research Square · 28 Aug 2026 · Preprint
Physical function
upin humans1Low certainty
1 study
Physical function
upin humans1Low certainty
Blood flow restriction training improves physical function in humans (p-value <0.05).
Human trialend-stage chronic kidney disease on hemodialysis8 weeksn = 36
Effect of Intradialytic Blood Flow Restriction Training on Functional Capacity, Estimated Glomerular Filtration Rate and Health-Related Quality of Life in Patients on Hemodialysis: A Randomized Controlled Trial · Research Square · 28 Aug 2026 · Preprint
Estimated glomerular filtration rate
upin humans1Low certainty
1 study
Estimated glomerular filtration rate
upin humans1Low certainty
Blood flow restriction training improves estimated glomerular filtration rate in humans (p-value <0.05).
Human trialend-stage chronic kidney disease on hemodialysis8 weeksn = 36
Effect of Intradialytic Blood Flow Restriction Training on Functional Capacity, Estimated Glomerular Filtration Rate and Health-Related Quality of Life in Patients on Hemodialysis: A Randomized Controlled Trial · Research Square · 28 Aug 2026 · Preprint
Fractional anisotropy
upin humans1Low certainty
1 study
Fractional anisotropy
upin humans1Low certainty
Blood flow restriction training increases fractional anisotropy in humans.
Human trialthree-group trialparietal region12 weeksmalesn = 48
Differential Effects of Blood-Flow Restriction and High-Intensity Resistance Training on Cortical Thickness and White Matter Integrity in Older Men: A Three-Group Randomized Controlled Trial · Brain sciences · 28 Jul 2026
Modified Barthel Index
upin humans1Low certainty
1 study
Modified Barthel Index
upin humans1Low certainty
Blood flow restriction training improves Modified Barthel Index in humans.
Human trialhospitalized older adults with sarcopenia, compared with resistance training3 times per week12 weeksn = 40
[Effects of Blood Flow Restriction Training on Muscle Strength and Physical Function in Older Adults With Sarcopenia] · Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 20 Jul 2026
Timed Up-and-Go
upin humans1Low certainty
1 study
Timed Up-and-Go
upin humans1Low certainty
Blood flow restriction training improves Timed Up-and-Go in humans.
Human trialhospitalized older adults with sarcopenia, compared with resistance training3 times per week12 weeksn = 40
[Effects of Blood Flow Restriction Training on Muscle Strength and Physical Function in Older Adults With Sarcopenia] · Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 20 Jul 2026
Gait speed
upin humans1Low certainty
1 study
Gait speed
upin humans1Low certainty
Blood flow restriction training improves gait speed in humans.
Human trialhospitalized older adults with sarcopenia, compared with resistance training3 times per week12 weeksn = 40
[Effects of Blood Flow Restriction Training on Muscle Strength and Physical Function in Older Adults With Sarcopenia] · Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 20 Jul 2026
Short Physical Performance Battery
upin humans1Low certainty
1 study
Short Physical Performance Battery
upin humans1Low certainty
Blood flow restriction training improves Short Physical Performance Battery in humans.
Human trialhospitalized older adults with sarcopenia, compared with resistance training3 times per week12 weeksn = 40
[Effects of Blood Flow Restriction Training on Muscle Strength and Physical Function in Older Adults With Sarcopenia] · Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 20 Jul 2026
Grip strength
upin humans1Low certainty
1 study
Grip strength
upin humans1Low certainty
Blood flow restriction training improves grip strength in humans ([25.25 ± 5.34] kg vs. [21.66 ± 5.19] kg).
Human trialhospitalized older adults with sarcopenia, compared with resistance training3 times per week12 weeksn = 40
[Effects of Blood Flow Restriction Training on Muscle Strength and Physical Function in Older Adults With Sarcopenia] · Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 20 Jul 2026