Sex hormones
Biomarker1 paper
- Animals1
Funding
National Heart, Lung, and Blood InstituteUS$2.4mNational Institute on AgingUS$792k3 grants since 2023
National Institute on AgingUniversity of MinnesotaUS$792k2026–2031
National Heart, Lung, and Blood InstituteUniversity of Vermont & St Agric CollegeUS$608k2023–2028
Postmenopausal androgens, sex hormone binding globulin, and cardiovascular risk: a cohort study
National Heart, Lung, and Blood InstituteKaiser Foundation Research InstituteUS$1.8m2026–2028
Latest
39Insulin resistance rose faster around menopause
For a modelled reference woman, an insulin resistance measure rose 4.3% yearly during the transition, compared with 1.2% before and 0.9% after.For a modelled reference woman, an insulin resistance measure rose 4.3% yearly during the transition, compared with 1.2% before and 0.9% after.
Sex hormone-binding globulin raises lumbar fracture risk
Genetically higher SHBG increased lumbar fracture risk with an odds ratio of 1.201 in FinnGen and 1.005 in UK Biobank, mediated primarily by bone…Genetically higher SHBG increased lumbar fracture risk with an odds ratio of 1.201 in FinnGen and 1.005 in UK Biobank, mediated primarily by bone density.
Oestradiol levels do not predict heart events in older women
In 5,535 women aged 70 and older, endogenous oestradiol concentrations showed no association with major cardiovascular events or all-cause mortality…In 5,535 women aged 70 and older, endogenous oestradiol concentrations showed no association with major cardiovascular events or all-cause mortality over 4.5 years of follow-up.