PPARγ

Biomarker

1 paper

Animals1

Latest

17 in 12 months

Journal of Lipid Research12 Oct

Wnt-PPARγ Seesaw Mechanism Mediates the Perilipin 2-to-1 Dominance Shift in Engineered Adipose Tissue Regeneration

Experiments in miceWnt/β-catenin signalling

Paper

bioRxiv30 Sep

A PPAR-gamma counterpart protects worm neurons by coordinating lipids and mitochondria

Researchers show that SEX-1 regulates sphingolipid metabolism and mitochondrial quality control in Caenorhabditis elegans, but its protective activity declines with age.Researchers show that SEX-1 regulates sphingolipid metabolism and mitochondrial quality control in Caenorhabditis elegans, but its protective activity declines with age.

Preprint: experiments in wormsMitochondrion

Paper

Aging Cell26 Sep

Deleting liver growth hormone receptors accelerates aging phenotypes and shortens lifespan in mice

The loss of hepatic growth hormone signaling disrupts lipid metabolism and causes mitochondrial damage that can be counteracted by inhibiting PDK4.The loss of hepatic growth hormone signaling disrupts lipid metabolism and causes mitochondrial damage that can be counteracted by inhibiting PDK4.

Experiments in miceGrowth hormone axis

Paper

Angiogenesis26 Sep