Neural Regeneration Research
Mechanism of action of synaptic mitochondrial damage in delayed cognitive recovery
Experiments in miceSynapse
Papers on pores
304 papers13 new in 30 days
Thursday, March 27
Sunday, March 23
International Journal of Biological Macromolecules
Immp2l gene knockout induces granulosa cell senescence by activation of cGAS-STING pathway via TFAM-mediated mtDNA leakage
Experiments in mouse cellscGAS–STING signaling
Monday, March 3
bioRxiv
The nuclear pore complex connects energy sensing to transcriptional plasticity in longevity
Preprint: experiments in wormsMechanisms
Thursday, February 6
Thursday, December 19
The Journals of Gerontology, Series A
Senolysis by GLS1 Inhibition Ameliorates Kidney Aging by Inducing Excessive mPTP Opening Through MFN1
Experiments in miceKidney
Wednesday, December 11
Free Radical Biology & Medicine
Spermidine alleviates diabetic periodontitis by reversing human periodontal ligament stem cell senescence via mitophagy
Experiments in miceSpermidine
Saturday, December 7
Biophysical Chemistry
Fifty-hertz magnetic fields induce DNA damage through activating mPTP associated mitochondrial permeability transition in senescent human fetal lung fibroblasts
Experiments in human cellsDNA damage response
Tuesday, December 3
eLife
TPR is required for cytoplasmic chromatin fragment formation during senescence
Experiments in human cellsCellular senescence
Monday, December 2
Acta Pharmacologica Sinica
Nicotinamide mononucleotide protects septic hearts in mice via preventing cyclophilin F modification and lysosomal dysfunction
Experiments in miceNicotinamide mononucleotide
Saturday, October 26
Friday, October 25
The EMBO Journal
Cyclophilin D plays a critical role in the survival of senescent cells
Experiments in human cellsCellular senescence
Wednesday, October 16
International Journal of Molecular Sciences
Biology of Healthy Aging: Biological Hallmarks of Stress Resistance Related and Unrelated to Longevity in Humans
Computational studyMechanisms
International Journal of Biological Macromolecules
Photo-crosslinked hyaluronic acid hydrogels designed for simultaneous delivery of mesenchymal stem cells and tannic acid: Advancing towards scarless wound healing
Experiments in ratsSkin
Monday, October 14
Calcified Tissue International
Sex-Specific Association Patterns of Bone Microstructure and Lower Leg Arterial Calcification
Cohort study of 132 peopleVascular calcification
Tuesday, October 1
bioRxiv
Calcium Homeostasis Modulator 2 Constitutes an ATP-regulation Pore in Mitochondria
Preprint: experiments in miceMitochondrion
Friday, September 27
Biological Reviews of the Cambridge Philosophical Society
Protection of the genome and the central exome by peripheral non-coding DNA against DNA damage in health, ageing and age-related diseases
ReviewDNA damage response
Free Radical Biology & Medicine
STING regulates aging-related osteoporosis by mediating the Hk2-Vdac1 mitochondrial axis
Experiments in animalsSTING1
Thursday, August 29
International Journal of Molecular Sciences
Interdependence between Nuclear Pore Gatekeepers and Genome Caretakers: Cues from Genome Instability Syndromes
ReviewDNA damage response
Saturday, August 24
Thursday, August 8
Journal of Advanced Research
Loss of Nup155 promotes high fructose-driven podocyte senescence by inhibiting INO80 mRNA nuclear export
Experiments in ratsInterventions
Tuesday, July 30
Artificial Organs
Design and simulation of a microfluidics-based artificial glomerular ultrafiltration unit to reduce cell-induced fouling
Computational studyInterventions
Thursday, July 11
Mechanisms of Ageing and Development
A mechanistic analysis of metformin's biphasic effects on lifespan and healthspan in C. elegans: Elixir in youth, poison in elder
Experiments in wormsMetformin
Monday, May 20
Clinical, Cosmetic and Investigational Dermatology
Facial Skin Aging Characteristics of the Old-Perceived Age in a 20-40 Years Old Chinese Female Population
Cross-sectional study of 400 peopleBiomarkers
Monday, May 13
Journal of Nanobiotechnology
Mesoporous MOFs with ROS scavenging capacity for the alleviation of inflammation through inhibiting stimulator of interferon genes to promote diabetic wound healing
Experiments in animalsSkin
Free Radical Biology & Medicine
PARP1 inhibition prevents oxidative stress in age-related hearing loss via PAR-Ca²⁺-AIF axis in cochlear strial marginal cells
Experiments in ratsOxidative stress and ROS signaling
Tuesday, April 30
International Journal of Cosmetic Science
Topical application of retinyl propionate, 4 hexyl resorcinol, and niacinamide reverses molecular and clinical features of ageing
Randomized trial in peopleInterventions