Exercise training

1. Exercise training increases HDL cholesterol in humans.

   “Evidence from two trials suggested that exercise training may increase HDL-C levels”

   Human trialin people living with HIV

   Dietary counselling and exercise training for lipid management in people living with HIV: A systematic review and meta-analysis

   HIV medicine·17 Aug 2026

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1. Exercise training increases DNA methylation in humans (14.2% to 16.5%).

   “showed increased DNA methylation after 8-weeks of training (14.2% to 16.5%, P<0.05)”

   Human trialskeletal muscle8 weeks

   MALAT1 Is an Exercise-Responsive Regulatory RNA Associated with Metabolic Traits

   ADA Scientific Sessions 2026 abstract·5 Jun 2026

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1. Exercise training increases 6-minute walk distance in humans (11%, P=.005).

   “At follow-up, the 6-MWT distance was higher than at the baseline in both the ET (11%, P=.005) and AC (9%, P=.004) groups.”

   Human trialheart failure with preserved ejection fraction16 weeksn = 23

   Association Between 6-Minute Walk Test Distance and Objective Variables of Functional Capacity After Exercise Training in Elderly Heart Failure Patients With Preserved Ejection Fraction: A Randomized Exercise Trial

   Archives of physical medicine and rehabilitation·28 Sep 2016

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1. Exercise training increases ventilatory threshold in humans (11%, P=.001).

   “In contrast, V ̇o2peak and VT values increased in the ET group (19% and 11%, respectively; P=.001)”

   Human trialheart failure with preserved ejection fraction16 weeksn = 23

   Association Between 6-Minute Walk Test Distance and Objective Variables of Functional Capacity After Exercise Training in Elderly Heart Failure Patients With Preserved Ejection Fraction: A Randomized Exercise Trial

   Archives of physical medicine and rehabilitation·28 Sep 2016

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1. Exercise training increases peak oxygen uptake in humans (19%, P=.001).

   “In contrast, V ̇o2peak and VT values increased in the ET group (19% and 11%, respectively; P=.001)”

   Human trialheart failure with preserved ejection fraction16 weeksn = 23

   Association Between 6-Minute Walk Test Distance and Objective Variables of Functional Capacity After Exercise Training in Elderly Heart Failure Patients With Preserved Ejection Fraction: A Randomized Exercise Trial

   Archives of physical medicine and rehabilitation·28 Sep 2016

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1. Exercise training increases flow-mediated dilation in humans (SMD 0.48, P = 0.008).

   “After data pooling, FMD was higher in athletes than that in control groups (SMD, 0.48; P = 0.008).”

   Review

   Flow-mediated dilation in athletes: influence of aging

   Medicine and science in sports and exercise·1 Nov 2014

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1. Exercise training decreases overall mortality in humans.

   “exercise training can clearly improve the functional capacity of patients and reduce overall mortality by decreasing the risk of sudden death.”

   ReviewManifest coronary artery disease

   Physical inactivity: a cardiovascular risk factor

   Indian journal of medical sciences·1 Jan 2009

1. Exercise training improves functional capacity in humans.

   “Once coronary artery disease has become manifest, exercise training can clearly improve the functional capacity of patients”

   ReviewManifest coronary artery disease

   Physical inactivity: a cardiovascular risk factor

   Indian journal of medical sciences·1 Jan 2009

1. Exercise training increases VO2max in humans.

   “individuals in this age range can increase their VO2max in response to training”

   Reviewmen and womens

   Effect of training on the decline of VO2max with aging

   Federation proceedings·1 Apr 1987

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