No phaseStatus unknown
Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER)
- Sponsor
- Finnish Institute for Health and Welfare (Government)
- Enrolment
- 1,200 planned
- Conditions
- Cognitive Impairment; Dementia
- Interventions
- Nutritional guidance; Exercise; Cognitive training; Reduction of vascular risk factors
- Ages
- adults, older adults
- Registry
- NCT01041989
From the registry
This multi-center (6 sites: Helsinki, Kuopio, Oulu, Seinäjoki, Turku, Vantaa) intervention study aims to prevent cognitive impairment, dementia and disability in 60-77 year old persons at an increased dementia risk. The 2-year multi-domain life-style intervention includes nutritional guidance, exercise, cognitive training, increased social activity, and intensive monitoring and management of metabolic and vascular risk factors. The primary outcome is cognitive impairment measured by a sensitive Neuropsychological Test Battery (NTB), and Stroop and Trail Making tests to capture early cognitive impairment typical for both Alzheimer's disease and vascular dementia. We hypothesize that the multi-domain intervention will reduce cognitive impairment in the study group compared to the control group during the initial 2-year intervention period and reduce dementia incidence after the extended follow-up (until at least 300 participants have developed dementia).
Primary outcomes
- Cognitive impairment assessed with a Neuropsychological Test Battery, and Stroop and Trail Making tests.