1 paper
In mice lacking ovaries, the targeted carrier delivered raloxifene to bone tissue and improved bone formation and structural integrity compared with the free drug.In mice lacking ovaries, the targeted carrier delivered raloxifene to bone tissue and improved bone formation and structural integrity compared with the free drug.
In mice lacking ovaries to mimic estrogen loss, deleting the Camkk1 gene from bone-degrading cells attenuated the loss of spongy bone.In mice lacking ovaries to mimic estrogen loss, deleting the Camkk1 gene from bone-degrading cells attenuated the loss of spongy bone.
In a mouse model of osteoporosis, silencing a gene or inhibiting its protein reduced the activity of cells that break down bone.In a mouse model of osteoporosis, silencing a gene or inhibiting its protein reduced the activity of cells that break down bone.
A titanium surface promoted bone formation around implants and improved spongy bone structure in an experiment in rats with age-related osteoporosis.A titanium surface promoted bone formation around implants and improved spongy bone structure in an experiment in rats with age-related osteoporosis.
An experiment in mice whose ovaries had been removed found that engineered, bone-targeting particles also reduced pain-related behaviours.An experiment in mice whose ovaries had been removed found that engineered, bone-targeting particles also reduced pain-related behaviours.
In ovariectomized mice, six weeks of treatment with pH-responsive puerarin nanoparticles restored trabecular bone architecture and increased bone mineral density.In ovariectomized mice, six weeks of treatment with pH-responsive puerarin nanoparticles restored trabecular bone architecture and increased bone mineral density.