An animal experiment compared scans with brain tissue in young and older squirrel monkeys, linking an imaging measure to amyloid vessel disease and tissue injury.An animal experiment compared scans with brain tissue in young and older squirrel monkeys, linking an imaging measure to amyloid vessel disease and tissue injury.
Different upper spinal cord measurements peaked at ages 29.7–44.1 years in reference charts based on scans of 10,159 healthy people aged 8–85.Different upper spinal cord measurements peaked at ages 29.7–44.1 years in reference charts based on scans of 10,159 healthy people aged 8–85.
Preprint: cross-sectional study of 10,159 peopleBiomarkers
An observational analysis of human brain tissue compared gene activity and cell proportions across normal cognition, disease-related aging and dementia.An observational analysis of human brain tissue compared gene activity and cell proportions across normal cognition, disease-related aging and dementia.
An experiment in twelve-month-old mice found better learning and memory alongside more immature nerve cells and greater insulation around nerve fibres.An experiment in twelve-month-old mice found better learning and memory alongside more immature nerve cells and greater insulation around nerve fibres.
Profiling lysosomal fractions from mouse cortex from 3 to 24 months revealed an accumulation of myelin-derived glycosphingolipids that was most pronounced in microglia.Profiling lysosomal fractions from mouse cortex from 3 to 24 months revealed an accumulation of myelin-derived glycosphingolipids that was most pronounced in microglia.
Researchers linked poor auditory nerve synchrony and myelin degradation to amplified communication difficulties in older humans, beyond standard hearing thresholds.Researchers linked poor auditory nerve synchrony and myelin degradation to amplified communication difficulties in older humans, beyond standard hearing thresholds.
A preprint using transcriptomic, histological and ultrastructural analyses of killifish optic nerves shows aging brings reduced myelin thickness and immune-responsive…A preprint using transcriptomic, histological and ultrastructural analyses of killifish optic nerves shows aging brings reduced myelin thickness and immune-responsive glia.