Experiments in mice found that azilsartan reduced muscle fibre loss and declines in grip strength and exercise capacity when a hormone induced muscle wasting.Experiments in mice found that azilsartan reduced muscle fibre loss and declines in grip strength and exercise capacity when a hormone induced muscle wasting.
Experiments in mice with angiotensin II-induced muscle atrophyMuscle
Limit: The experiments tested hormone-induced wasting, not naturally occurring age-related muscle loss
In 45 patients with heart failure with preserved ejection fraction, diet and exercise partially reversed altered gene activity and DNA packaging in muscle.In 45 patients with heart failure with preserved ejection fraction, diet and exercise partially reversed altered gene activity and DNA packaging in muscle.
The treatment reduced oxidative stress, suppressed inflammation, and remodeled the gut microbiome in naturally aging mice while prolonging survival in nematodes.The treatment reduced oxidative stress, suppressed inflammation, and remodeled the gut microbiome in naturally aging mice while prolonging survival in nematodes.
Researchers identified PNPLA7 as an essential regulator of phosphatidylcholine catabolism necessary for maintaining mouse muscle fiber size and endurance.Researchers identified PNPLA7 as an essential regulator of phosphatidylcholine catabolism necessary for maintaining mouse muscle fiber size and endurance.