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Nature Communications

Targeting a cell regulator reduced bone loss in mice

In a mouse model of osteoporosis, silencing a gene or inhibiting its protein reduced the activity of cells that break down bone.In a mouse model of osteoporosis, silencing a gene or inhibiting its protein reduced the activity of cells that break down bone.

Oxr1 is upregulated during osteoclast differentiation and osteoporosis pathogenesis.
Experiments in miceBones and joints

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