2 papers4 findings
Human cohort research links higher platelet-to-HDL cholesterol ratio and platelet count to incident stroke in initially stroke-free people with hypertension. In people with hypertension, remnant cholesterol inflammation index estimates differ: one confidence interval includes no association, while another indicates higher stroke risk.
Remnant cholesterol inflammation index
no changein humans1upin humans1HR 1.06–1.6
Remnant cholesterol inflammation index is associated with incident stroke in humans (HR 1.06, 95% CI 0.99-1.14).
Humanshypertensionmedian follow-up of 9.08 yearsn = 3,823
Frontiers in cardiovascular medicine24 Aug 2026
Remnant cholesterol inflammation index raises the risk of incident stroke in humans (HR 1.60, 95% CI 1.23-2.08).
Humanshypertensionmedian follow-up of 9.08 yearsn = 3,823
Frontiers in cardiovascular medicine24 Aug 2026
Platelet count
upin humans1HR 1.16
Platelet count is associated with incident stroke in humans (HR 1.16 per 1-SD increase, 95% CI 1.07–1.25).
HumansHypertension and stroke-free at baseline2011–2020n = 3,963
The Journal of international medical research8 Oct 2026
Platelet-to-high-density lipoprotein cholesterol ratio
upin humans1HR 1.15
Platelet-to-high-density lipoprotein cholesterol ratio is associated with incident stroke in humans (HR 1.15 per 1-SD increase, 95% CI 1.07–1.24).
HumansHypertension and stroke-free at baseline; Model 3 adjustment2011–2020n = 3,963
The Journal of international medical research8 Oct 2026
More on Platelet-to-high-density lipoprotein cholesterol ratio
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High glycation index was associated with increased stroke risk at an adjusted hazard ratio of 1.392, which remained 1.333 after HbA1c adjustment.High glycation index was associated with increased stroke risk at an adjusted hazard ratio of 1.392, which remained 1.333 after HbA1c adjustment.
Each 1-standard deviation higher CXCL10 was linked to 20% greater stroke risk over a median follow-up of 14 years.Each 1-standard deviation higher CXCL10 was linked to 20% greater stroke risk over a median follow-up of 14 years.
Impaired glucose tolerance carried a hazard ratio of 1.58 and diabetes 1.69 for first stroke compared with normal tolerance, while mortality showed no link.Impaired glucose tolerance carried a hazard ratio of 1.58 and diabetes 1.69 for first stroke compared with normal tolerance, while mortality showed no link.
In adults aged 60 to 69, low global cognition carried a stroke hazard ratio of 1.86 compared with the highest tertile over 12.3 years.In adults aged 60 to 69, low global cognition carried a stroke hazard ratio of 1.86 compared with the highest tertile over 12.3 years.