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bioRxiv

A protein supports force in stretched animal muscle fibres

Experiments in animal muscle fibres found that reducing the protein plakoglobin impaired the extra activation of force-producing structures as their contractile units…Experiments in animal muscle fibres found that reducing the protein plakoglobin impaired the extra activation of force-producing structures as their contractile units lengthened.

Preprint: experiments in animalsMuscle
Journal of Hypertension

A protein raised aging markers in lab-grown placental cells

Experiments using a human placental cell line also found reduced invasion into surrounding material when researchers increased the protein BCL10.Experiments using a human placental cell line also found reduced invasion into surrounding material when researchers increased the protein BCL10.

Experiments in human cellsMechanisms
Advanced Science

Drug-carrying particles reduced bone loss in mice

In an animal experiment, drug-carrying particles preserved bone structure and enhanced bone formation in mice whose ovaries had been removed.In an animal experiment, drug-carrying particles preserved bone structure and enhanced bone formation in mice whose ovaries had been removed.

Experiments in miceBones and joints
Journal of Orthopaedic Surgery

Glaucoma eye-drop groups differed in osteoporosis risk

Osteoporosis was diagnosed in 13.3% of patients prescribed drops such as latanoprost, compared with 8.9% prescribed drops such as pilocarpine.Osteoporosis was diagnosed in 13.3% of patients prescribed drops such as latanoprost, compared with 8.9% prescribed drops such as pilocarpine.

Cohort study of 6,743 peoplePrimary open-angle glaucoma
Journal of Advanced Research

Bile acid corrected abnormal fat-cell formation in human cells

Lab experiments in bone marrow cells from patients with postmenopausal osteoporosis also found reduced senescence, a state in which cells stop dividing.Lab experiments in bone marrow cells from patients with postmenopausal osteoporosis also found reduced senescence, a state in which cells stop dividing.

Experiments in miceInterventions