Cognitive reserve

Biomarker2 papers2 findings

  • Human trial1
  • Humans1

Associations

2

Applied cognitive activities of daily living impairment

downin humans1

1 study
  1. Cognitive reserve is associated with applied cognitive activities of daily living impairment in humans (49% less impairment, 95%CI: 0.26-0.97).

    Humans81.3% femalesn = 1,571

    Cognitive reserve and everyday functioning in cognitively unimpaired older adults: evidence from the CAN-PROTECT study · The journals of gerontology. Series A, Biological sciences and medical sciences · 12 Sep 2026

Activities of daily living impairment

downin humans1

1 study
  1. Cognitive reserve is associated with activities of daily living impairment in humans (count ratio=0.58, 95%CI: 0.36-0.94).

    Humans81.3% femalesn = 1,571

    Cognitive reserve and everyday functioning in cognitively unimpaired older adults: evidence from the CAN-PROTECT study · The journals of gerontology. Series A, Biological sciences and medical sciences · 12 Sep 2026

Funding

National Institute on AgingUS$3m6 grants since 2022

Latest

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Alzheimer's Research & TherapyHumans

Education links to better cognition independent of brain pathology

Across two aging cohorts spanning normal cognition to mild Alzheimer’s disease, higher education tracked with better cognitive performance even after…Across two aging cohorts spanning normal cognition to mild Alzheimer’s disease, higher education tracked with better cognitive performance even after adjusting for multimodal brain pathology.