IL-6 secretion

2 papers2 findings

Animals1
Cells1

Interventions

1

Multi-ingredient nutraceuticals

downin mouse cells1

1 study

Multi-ingredient nutraceuticals decrease IL-6 secretion in mouse cells.
“reducing nuclear size, ROS release, and IL-6 secretion in senescent fibroblasts.”
Cellssenescent fibroblasts12 pro-longevity natural compoundsfibroblast
Rescuing Healthspan in Obese, Aged Mice: A Comparison between Multi-Ingredient Nutraceuticals and Senolytic Interventions
Preprints.org31 Dec 2025Preprint

More on Multi-ingredient nutraceuticals

Associations

1

G2 cell-cycle arrest

upin human cells1

1 study

G2 cell-cycle arrest is associated with IL-6 secretion in human cells.
“We determined that G2-arrested senescent cells secrete more IL-6 and are more sensitive to ABT263 than G1-arrested cells.”
CellsG2-arrested versus G1-arrested senescent cellsprimary human endothelial cells and fibroblasts
Senescent cell heterogeneity and responses to senolytic treatment are related to cell cycle status during senescence induction
Aging7 Aug 2025

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Mechanisms of Ageing and Development7 Sep

Attenuating monocytic inflammaging via the miR-146a/TLR4 axis: Characterization and bioactivity of a triterpenoid-rich callus phytocomplex

Experiments in human cellsInterventions

Cellular Oncology23 Mar

Targeting senescence-like tumor-associated macrophages sensitizes chemotherapy in triple-negative breast cancer

Experiments in miceInterventions

Stem Cell Research & Therapy17 Feb

Distinct decidualization and senomorphic responses in endometrial vs. menstrual blood stem/stromal cells: implications for reproductive therapies

Experiments in human cellsSenomorphics

JMIR Research Protocols13 Jan

The Role of Iron-Overloaded Macrophages in Mesenchymal Stem Cell Senescence and Anemia in Myelodysplastic Syndromes: Protocol for an In Vitro Study

Study protocolCellular senescence

Preprints.org31 Dec

Rescuing Healthspan in Obese, Aged Mice: A Comparison between Multi-Ingredient Nutraceuticals and Senolytic Interventions

Preprint: experiments in miceInterventions

Aging Pathobiology and Therapeutics29 Sep

Pharmacologic activation of Δ133p53α reduces cellular senescence in progeria patients-derived cells

Experiments in cellsInterventions

Aging8 Aug

Senescent cell heterogeneity and responses to senolytic treatment are related to cell cycle status during senescence induction

Experiments in human cellsSenolytics

bioRxiv6 Aug

Pharmacologic activation of Δ133p53α reduces cellular senescence in progeria patients-derived cells

Preprint: experiments in cellsInterventions

Nature Cell Biology13 Jul

Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion

Experiments in human cellsDNA damage response