Papers on hedgehog
116 papers3 new in 30 days
Tuesday, April 25
Tuesday, April 11
Saturday, March 4
American Journal of Human Genetics
Dynamic chromatin accessibility tuning by the long noncoding RNA ELDR accelerates chondrocyte senescence and osteoarthritis
Experiments in miceCellular senescence
Sunday, February 26
Saturday, February 11
Frontiers in Medicine
Senescent renal tubular epithelial cells activate fibroblasts by secreting Shh to promote the progression of diabetic kidney disease
Experiments in miceCellular senescence
Monday, November 28
International Journal of Molecular Sciences
miR-18a-5p Is Involved in the Developmental Origin of Prostate Cancer in Maternally Malnourished Offspring Rats: A DOHaD Approach
Experiments in ratsMechanisms
Saturday, November 26
Basic and Clinical Neuroscience
Reprogramming by Cytosolic Extract of Human Embryonic Stem Cells to Improve Dopaminergic Differentiation Potential of Human Adipose Tissue-derived Stem Cells
Experiments in human cellsInterventions
Thursday, October 20
Saturday, September 24
Friday, June 10
Research Square
A novel transcript of LncRNA ELDR promotes chondrocyte senescence and osteoarthritis progression by tuning chromosomal dynamics
Preprint: experiments in miceOsteoarthritis
Wednesday, May 11
Molecular Human Reproduction
Uterine-specific SIRT1 deficiency confers premature uterine aging and impairs invasion and spacing of blastocyst, and stromal cell decidualization, in mice
Experiments in miceSIRT1
Wednesday, May 4
Developmental Cell
Single-cell analysis of human testis aging and correlation with elevated body mass index
Cross-sectional study of 44,000 peopleReproductive system
Saturday, March 19
Nature Communications
Primary cilia on muscle stem cells are critical to maintain regenerative capacity and are lost during aging
Experiments in miceCilium
Saturday, February 12
Thursday, January 6
Aging Cell
Aging reduces liver resiliency by dysregulating Hedgehog signaling
Experiments in miceMechanisms
Tuesday, January 4
Neurobiology of Disease
Primary cilia and ciliary signaling pathways in aging and age-related brain disorders
ReviewCilium
Saturday, December 25
International Journal of Molecular Sciences
Transient Activation of Hedgehog Signaling Inhibits Cellular Senescence and Inflammation in Radiated Swine Salivary Glands through Preserving Resident Macrophages
Experiments in pigsVEGF signaling
Tuesday, December 21
Acta Obstetricia et Gynecologica Scandinavica
Cyclic activity of signal transduction pathways in fimbrial epithelium of the human fallopian tube
Study in peopleMechanisms
Frontiers in Cell and Developmental Biology
Sulforaphane Targets TRA-1/GLI Upstream of DAF-16/FOXO to Promote C. elegans Longevity and Healthspan
Experiments in wormsInterventions
Tuesday, December 7
Journal of Bone and Mineral Research
Hedgehog Signaling Controls Bone Homeostasis by Regulating Osteogenic/Adipogenic Fate of Skeletal Stem/Progenitor Cells in Mice
Experiments in animalsMechanisms
Wednesday, October 20
bioRxiv
Single-Cell Analysis of Human Testis Aging, and Impact of Elevated Body Mass Index
Preprint: cross-sectional study of 44,000 peopleReproductive system
Friday, October 15
Frontiers in Cell and Developmental Biology
Sonic Hedgehog Induces Mesenchymal Stromal Cell Senescence-Associated Secretory Phenotype and Chondrocyte Apoptosis in Human Osteoarthritic Cartilage
Experiments in human cellsApoptosis
Wednesday, August 18
Acta Neuropathologica Communications
Forebrain Shh overexpression improves cognitive function and locomotor hyperactivity in an aneuploid mouse model of Down syndrome and its euploid littermates
Experiments in miceDown syndrome
Sunday, August 15
Saturday, August 14
Stem Cell Research
Generation of striatal neurons from human induced pluripotent stem cells by controlling extrinsic signals with small molecules
Experiments in cellsInterventions
Tuesday, July 27
Frontiers in Molecular Biosciences
The Role of Sonic Hedgehog Pathway in the Development of the Central Nervous System and Aging-Related Neurodegenerative Diseases
ReviewMechanisms
Tuesday, April 20
Current Medical Science
Sulforaphane as a Promising Natural Molecule for Cancer Prevention and Treatment
ReviewCancer
Saturday, February 13
Tuesday, February 2
Tuesday, December 1
Stem Cells
GATA6 regulates aging of human mesenchymal stem/stromal cells
Experiments in human cellsCell cycle regulation