FRAIL

Papers on FRAIL

10,425 papers222 new in 30 days

Sunday, October 25

Saturday, October 24

Friday, October 23

European Journal of Anaesthesiology

Frailty linked to complications after surgery in European adults

Frailty before surgery was linked to 2.35 times the adjusted odds of complications within 30 days, compared with no frailty.Frailty before surgery was linked to 2.35 times the adjusted odds of complications within 30 days, compared with no frailty.

Groups of upright patients stand beside a closed surgical wound and a larger open wound, with a brain bearing a dark spot near the larger group.
Cohort · 1,472 peoplePostoperative complications
Clinical Gastroenterology and Hepatology

Frailty improvement linked to survival in liver transplant candidates

Candidates whose frailty score improved by at least 0.4 had about 50% lower mortality than those who did not reach that improvement.Candidates whose frailty score improved by at least 0.4 had about 50% lower mortality than those who did not reach that improvement.

A large nodular liver sits above closely grouped dark blue-green people beside an exercising figure and a more widely spaced gray group.
Cohort · 352 peopleInterventions

Thursday, October 22

Research Square

Frailty links to distinct muscle and protein changes by sex

In 208 older adults, frailty was linked to muscle and bone loss in females, while males showed lower leg strength and altered muscle protein breakdown.In 208 older adults, frailty was linked to muscle and bone loss in females, while males showed lower leg strength and altered muscle protein breakdown.

Group differences in muscle health and exercise capacity in the whole group, males, and females; peak leg torque extension (a), 6MWT distance (d), and lean soft tissue (g) in whole group, and peak…
Preprint: cross-sectional · 208 peopleMuscle

Wednesday, October 21

Tuesday, October 20

Archives of Public Health

Frailty changes linked to chronic disease risk in China

An observational study of 17,708 adults aged 40 or older linked worsening frailty to higher disease risks and improved frailty to lower risks.An observational study of 17,708 adults aged 40 or older linked worsening frailty to higher disease risks and improved frailty to lower risks.

Study analysis scheme.
Cohort studyPopulations

Monday, October 19

The Journal of Frailty & Aging

Midlife activity linked to lower odds of frailty or its early signs

Persistent or rising midlife activity was associated with 80% and 79% lower odds of pre-frailty or frailty, respectively, than persistent inactivity after 22 years.Persistent or rising midlife activity was associated with 80% and 79% lower odds of pre-frailty or frailty, respectively, than persistent inactivity after 22 years.

Physical activity trajectories of participants at baseline, 5 years, and 10 years of follow-up, and the relevant prevalence of frailty or prefrailty at 22 years for each of the following trajectory…
Cohort studyPopulations
Diabetic Medicine

Diabetes drugs linked to fewer harms but more genital infections

A Taiwanese observational study found urinary tract infection rates of 23.84 versus 27.88 per 1,000 person-years for two diabetes drug classes.A Taiwanese observational study found urinary tract infection rates of 23.84 versus 27.88 per 1,000 person-years for two diabetes drug classes.

Kidney cross-sections show intact tissue above a vulva with dense infection spots, beside damaged tissue above a vulva with sparse spots.
Cohort studyGenital infections
Journal of Global Health

Frailty linked to fewer healthy working years at age 50

Estimated healthy working life at 50 was 11.87 years in robust adults, 7.34 in pre-frail adults and 3.77 in frail adults.Estimated healthy working life at 50 was 11.87 years in robust adults, 7.34 in pre-frail adults and 3.77 in frail adults.

HWLE and DHWLE at age 50 years by frailty, with 95% CIs for HWLE and Bonferroni-adjusted 95% CIs for DHWLE in parentheses.
Cohort · 180,314 peoplePopulations

Sunday, October 18